0104 areas
One-carbon metabolism
Methyl transfer by methionine synthase, linking the folate and methionine cycles.
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Research peptide
Vitamin B12
10mg
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Vitamin B12 (Methylcobalamin) 10mg
Methylcobalamin, the methyl form of vitamin B12, lyophilized. Sold in 10mg vials for laboratory research.
$16.00
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- 2-Day Priority Air: $13 flat anywhere in the US, or pick up in Medford.
- Tracking is emailed the moment your order ships.
- Research compounds are final sale; see the refund policy.
Lab sheet
Vitamin B12 details
Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.
Molecular Formula
C63H91CoN13O14P
Molar Mass
1344.4 g/mol
CAS Number
13422-55-4
Form
Lyophilized powder
Full data sheet+
- Purity
- A batch report is not published for this product. Contact ORP before ordering if you need one.
- Synonyms
- Methylcobalamin, mecobalamin, methyl-B12
- PubChem CID
- 10898559
- Storage (lyophilized)
- -20 °C, sealed, light-protected
For research use only. Not for human consumption.
Overview
About Vitamin B12
Vitamin B12 is a family of cobalt-containing compounds called cobalamins. Methylcobalamin is one of the two forms that work as coenzymes in mammalian cells: it carries the methyl group used by methionine synthase, the enzyme that turns homocysteine into methionine. It is not a peptide; ORP lists it with its research compounds.
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It has a molecular formula of C63H91CoN13O14P, a molar mass of 1344.4 g/mol and CAS number 13422-55-4; the full identifiers are in the lab sheet above. ORP supplies it as a lyophilized powder for in vitro and preclinical research only. It is not for human or animal use and is not intended to diagnose, treat, cure, or prevent any disease.
Vitamin B12 is one of the largest and most complex vitamins. Dorothy Hodgkin and colleagues worked out its three-dimensional structure by X-ray crystallography and reported it in Nature in 1956; she received the 1964 Nobel Prize in Chemistry for structures of important biological molecules, including B12.
The other coenzyme form, adenosylcobalamin, works in mitochondria with methylmalonyl-CoA mutase. Cyanocobalamin, the form most often used in supplements, is converted to these active forms in cells. Methylcobalamin is sensitive to light, which breaks the cobalt-methyl bond, so it is handled and stored protected from light.
Methylcobalamin, also called mecobalamin, is the active ingredient of medicines in some countries. This listing is a research compound for laboratory use, not a medicine.
Researchers usually confirm identity by mass spectrometry and UV-visible spectroscopy, and purity by HPLC. A third-party certificate of analysis is not published here for this product; contact ORP before ordering if your work needs particular identity or purity tests.
Research context
What Vitamin B12 is researched for
The areas where this compound appears in the published research literature.
Methodology
How Vitamin B12 is studied
01Method 1Published methylcobalamin work uses cultured cells including neurons, methionine synthase enzyme assays and rodent models, with readouts such as homocysteine…+
Published methylcobalamin work uses cultured cells including neurons, methionine synthase enzyme assays and rodent models, with readouts such as homocysteine and methionine levels, methylation markers and nerve-regeneration measures.
02Method 2Methylcobalamin is light-sensitive, so solutions are prepared and handled under low light.+
Methylcobalamin is light-sensitive, so solutions are prepared and handled under low light. Each research protocol sets its own model, controls, concentrations and handling; this listing supplies the compound, not a protocol.
Storage protocols
Vitamin B12 storage and handling
Lyophilized
-20°C
Long-term storage, as supplied
Reconstituted
2-8°C
In solution
Full handling protocol+
Store lyophilized methylcobalamin at -20°C, sealed and protected from light and moisture; it is light-sensitive. Let the vial reach room temperature before opening so moisture does not condense on the powder.
Reconstituted solutions are commonly held at 2-8°C in single-use aliquots, protected from light, to avoid repeated freeze-thaw cycles. Validate the solvent, concentration and use period for your own protocol.
Ordering & shipping
Buy Vitamin B12 online
Vitamin B12 for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $20. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
Vitamin B12 is supplied as lyophilized powder, for laboratory and research use only, not for human consumption.
FAQ
Vitamin B12 FAQ
What is methylcobalamin?
Methylcobalamin is the methyl form of vitamin B12 and one of its two coenzyme forms in cells. It carries the methyl group used by methionine synthase. ORP sells it for laboratory research only.
Is vitamin B12 a peptide?
No. Vitamin B12 is a cobalt-containing compound built around a corrin ring, not a chain of amino acids. ORP lists it with its research compounds.
What is the CAS number for methylcobalamin?
13422-55-4. Its PubChem compound ID is 10898559.
What is the difference between methylcobalamin and cyanocobalamin?
Both are vitamin B12. Methylcobalamin is one of the two coenzyme forms cells use; cyanocobalamin, common in supplements, carries a cyano group and is converted to the active forms in cells. This listing is methylcobalamin.
Why does methylcobalamin need protecting from light?
Light breaks the bond between the cobalt and the methyl group, converting methylcobalamin to hydroxocobalamin. Keep the vial and any solution away from light.
What does methylcobalamin research study?
Mainly one-carbon metabolism and methylation, homocysteine metabolism, and nerve cells and nerve regeneration in cell and rodent models. All of this is laboratory research.
Is this methylcobalamin third-party tested?
A third-party certificate of analysis is not published for this product. Contact ORP before ordering if your work needs particular identity or purity tests.
How should methylcobalamin be stored?
Keep the lyophilized powder at -20°C, sealed and protected from light and moisture. Reconstituted solutions are commonly kept at 2-8°C in single-use aliquots, away from light; validate the use period for your own protocol.
Is vitamin B12 for human use?
No. ORP sells methylcobalamin strictly as a laboratory research compound, not for human or animal consumption, and it is not intended to diagnose, treat, cure, or prevent any disease.
Research library