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Semax/Selank is a research blend of Semax and Selank, two heptapeptides studied in neurological research, supplied as a research nasal spray.
New product line: orders ship from Nov 9, then 2-Day Priority Air.
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A third-party certificate for Semax/Selank Nasal Spray is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.
Ask about a certificateFor research use only. Not for human consumption.
Semax/Selank is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute.
Semax is a heptapeptide analog of the ACTH(4-7) fragment with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Developed in Russia at the Institute of Molecular Genetics of the Russian Academy of Sciences, Semax was designed to retain the cognitive and neuroprotective properties associated with ACTH-derived peptides while eliminating their steroidogenic activity. It has been studied extensively in neuroscience research contexts.
Laboratory investigations have characterized Semax's interactions with the brain-derived neurotrophic factor (BDNF) signaling pathway. In rodent model studies, Semax exposure has been associated with increased BDNF and TrkB mRNA expression in hippocampal and cortical tissue, placing it within the growing field of neurotrophic factor research. Researchers have also examined its reported modulation of dopaminergic and serotonergic markers in preclinical neural models.
Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg), developed in Russia at the Institute of Molecular Genetics. With the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, Selank was designed to combine tuftsin-like biological activity with enhanced metabolic stability, as the Pro-Gly-Pro C-terminal extension confers resistance to proteolytic degradation.
In laboratory and preclinical research, Selank has been investigated for its effects on anxiolytic-like behavior in animal models, as well as for its interactions with the GABAergic system, brain-derived neurotrophic factor (BDNF) expression, and enkephalin metabolism. Research has also examined its putative immunomodulatory properties in the context of its tuftsin-derived sequence.
The areas where this compound appears in the published research literature.
In vitro, Semax is applied to primary cortical neuron cultures and neural stem cell preparations. Researchers measure neuronal survival following oxidative stress or excitotoxic challenge using MTT/resazurin viability assays, caspase activation profiling, and mitochondrial membrane potential indicators. TrkB pathway phosphorylation status is assessed by Western blot.
Neurobiological studies examine Selank's effects on gene and protein expression in brain tissue, quantifying BDNF, GABA receptor subunit levels, and enkephalin-degrading enzyme activity via RT-PCR, Western blot, and fluorometric enzyme assays. These studies map the molecular correlates of observed behavioral effects.
Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.
Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Semax/Selank Nasal Spray for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $100. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
Semax/Selank Nasal Spray is supplied as solution in a metered spray bottle, for laboratory and research use only, not for human consumption.
