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NAD+ Nasal Spray

NAD+ is the coenzyme studied in cellular-energy and mitochondrial research, supplied as a research nasal spray.

$85
Presale · ships by Mon, Nov 92-Day Priority Air anywhere in the US

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  • Presale: orders ship from Nov 9.
  • 2-Day Priority Air: $13 flat anywhere in the US, or pick up in Medford.
  • Tracking is emailed the moment your order ships.
  • Research compounds are final sale; see the refund policy.
Lab sheet

NAD+ Nasal Spray details

Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.

Certificate of analysis
Not published yet

A third-party certificate for NAD+ Nasal Spray is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.

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Molecular Formula
C21H27N7O14P2
Molar Mass
663.43 g/mol
CAS Number
53-84-9
Form
Solution in a metered spray bottle
Full data sheet+
Sizes
500mg
Purity
A batch report is not yet published for this format. Contact ORP before ordering if you need one.

For research use only. Not for human consumption.

Overview

About NAD+ Nasal Spray

NAD+ is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute.

Read more

NAD+ 500 (nicotinamide adenine dinucleotide, 500 mg formulation) provides research-grade NAD+ for laboratory investigation of cellular energy metabolism, mitochondrial function, and the diverse enzymatic reactions in which NAD+ serves as a critical coenzyme. NAD+ is a fundamental molecule in cellular biochemistry, functioning both as a hydride carrier in oxidation-reduction reactions and as a substrate for enzymes including sirtuins, PARPs, and CD38.

Research interest in NAD+ has grown substantially with the recognition that NAD+ levels decline with age in many tissue models and that restoring NAD+ availability influences a range of cellular processes including mitochondrial biogenesis, DNA repair, and inflammatory signaling. Laboratory studies use NAD+ preparations to investigate these pathways in cell culture and preclinical models.

Research-grade NAD+ 500 is utilized as a direct substrate in enzymatic assays, as a supplementation agent in cell culture experiments studying metabolic rescue, and in biochemical studies examining NAD+/NADH ratios and their relationship to cellular redox state and signaling.

Research context

What NAD+ Nasal Spray is researched for

The areas where this compound appears in the published research literature.

0103 areas

Cellular Energy Metabolism

NAD+ is a central coenzyme in glycolysis, the citric acid cycle, and oxidative phosphorylation; laboratory research examines how NAD+ availability influences mitochondrial respiration rates and ATP production efficiency in cell culture models.

0203 areas

Sirtuin Biology

Sirtuins are NAD+-dependent deacylases implicated in aging biology and metabolic regulation; research uses NAD+ supplementation to investigate how sirtuin activity responds to changes in NAD+ availability in preclinical models.

0303 areas

DNA Repair Research

PARP enzymes, which require NAD+ as a substrate, play critical roles in DNA damage repair; laboratory studies investigate the relationship between cellular NAD+ levels and the efficiency of PARP-mediated repair responses.

Methodology

How NAD+ Nasal Spray is studied

  1. 01Method 1In laboratory research, NAD+ is added to cell culture media or administered in preclinical animal models to examine the metabolic consequences of altered NAD+ availability.+

    In laboratory research, NAD+ is added to cell culture media or administered in preclinical animal models to examine the metabolic consequences of altered NAD+ availability. Researchers quantify intracellular NAD+ and NADH levels using cycling-based colorimetric assays or LC-MS/MS, and measure downstream pathway activity through sirtuin deacetylase assays, PARP activity assays, and mitochondrial respiration measurements via Seahorse XF analysis.

  2. 02Method 2In vitro enzymatic studies use purified recombinant enzymes (sirtuins, PARPs, CD38) with NAD+ as the substrate to characterize kinetic parameters (Km, Vmax)…+

    In vitro enzymatic studies use purified recombinant enzymes (sirtuins, PARPs, CD38) with NAD+ as the substrate to characterize kinetic parameters (Km, Vmax) and inhibitor profiles, providing fundamental biochemical data on how these enzymes interact with the NAD+ molecule.

Storage protocols

NAD+ Nasal Spray storage and handling

Full handling protocol+

Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.

Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.

Ordering & shipping

Buy NAD+ Nasal Spray online

NAD+ Nasal Spray for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $85. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.

NAD+ Nasal Spray is supplied as solution in a metered spray bottle, for laboratory and research use only, not for human consumption.

FAQ

NAD+ Nasal Spray FAQ

What format is NAD+ Nasal Spray?
NAD+ is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute. It is sold for laboratory research.
Is NAD+ Nasal Spray for human use?
No. Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Is a batch report available for NAD+ Nasal Spray?
A batch report is not yet published for this format. Contact ORP before ordering if you need one.
What role does NAD+ play in cellular metabolism research?
NAD+ is studied as a central coenzyme in cellular redox chemistry, serving as a hydride acceptor in catabolic pathways (glycolysis, beta-oxidation, the citric acid cycle) and as a donor in anabolic reductions. Its central metabolic position makes it a key target for studying energy metabolism in laboratory models.
How does NAD+ function as a substrate for sirtuin research?
Sirtuins catalyze NAD+-dependent protein deacylation reactions; for every deacylation event, one NAD+ molecule is consumed and nicotinamide is released. Research studies use NAD+ availability as a lever to modulate sirtuin activity in cell culture models, examining downstream effects on gene expression and mitochondrial function.
Research library

NAD+ Nasal Spray research guides

Optimum ReGen Peptides
Optimum ReGen Peptides

Optimum ReGen Peptides provides high-quality peptide compounds for laboratory research applications. All research products, including all peptides, are strictly for research purposes only and are not intended for human consumption.

Research products are intended for laboratory research purposes only. Not for human consumption. Our tallow skincare products are topical cosmetics for external use only. No product is intended to diagnose, treat, cure, or prevent any disease.

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