NAD+ 500 (nicotinamide adenine dinucleotide, 500 mg formulation) provides research-grade NAD+ for laboratory investigation of cellular energy metabolism, mitochondrial function, and the diverse enzymatic reactions in which NAD+ serves as a critical coenzyme. NAD+ is a fundamental molecule in cellular biochemistry, functioning both as a hydride carrier in oxidation-reduction reactions and as a substrate for enzymes including sirtuins, PARPs, and CD38.
Research interest in NAD+ has grown substantially with the recognition that NAD+ levels decline with age in many tissue models and that restoring NAD+ availability influences a range of cellular processes including mitochondrial biogenesis, DNA repair, and inflammatory signaling. Laboratory studies use NAD+ preparations to investigate these pathways in cell culture and preclinical models.
Research-grade NAD+ 500 is utilized as a direct substrate in enzymatic assays, as a supplementation agent in cell culture experiments studying metabolic rescue, and in biochemical studies examining NAD+/NADH ratios and their relationship to cellular redox state and signaling.