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Selank Nasal Spray

Selank is a synthetic tuftsin-analogue heptapeptide studied in neurological research, supplied as a research nasal spray.

$85
Presale · ships by Mon, Nov 92-Day Priority Air anywhere in the US

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  • Presale: orders ship from Nov 9.
  • 2-Day Priority Air: $13 flat anywhere in the US, or pick up in Medford.
  • Tracking is emailed the moment your order ships.
  • Research compounds are final sale; see the refund policy.
Lab sheet

Selank Nasal Spray details

Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.

Certificate of analysis
Not published yet

A third-party certificate for Selank Nasal Spray is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.

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Molecular Formula
C33H57N11O9
Molar Mass
751.88 g/mol
CAS Number
129954-34-3
Form
Solution in a metered spray bottle
Full data sheet+
Sizes
Nasal spray
Purity
A batch report is not yet published for this format. Contact ORP before ordering if you need one.

For research use only. Not for human consumption.

Overview

About Selank Nasal Spray

Selank is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute.

Read more

Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg), developed in Russia at the Institute of Molecular Genetics. With the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, Selank was designed to combine tuftsin-like biological activity with enhanced metabolic stability, as the Pro-Gly-Pro C-terminal extension confers resistance to proteolytic degradation.

In laboratory and preclinical research, Selank has been investigated for its effects on anxiolytic-like behavior in animal models, as well as for its interactions with the GABAergic system, brain-derived neurotrophic factor (BDNF) expression, and enkephalin metabolism. Research has also examined its putative immunomodulatory properties in the context of its tuftsin-derived sequence.

Selank represents a research model for studying the intersection of neuropeptide pharmacology and immune modulation, and has served as a tool in preclinical neuroscience to probe anxiety-related circuitry and peptidergic modulation of CNS function.

Research context

What Selank Nasal Spray is researched for

The areas where this compound appears in the published research literature.

0103 areas

Anxiolytic-Like Behavior in Preclinical Models

Selank has been studied in rodent anxiety models (elevated plus maze, open field test) to characterize its effects on anxiety-related behavioral endpoints, with investigators examining its interaction with GABA receptor systems.

0203 areas

BDNF Expression Research

Laboratory studies have investigated how Selank influences brain-derived neurotrophic factor (BDNF) expression in neuronal cell cultures and rodent brain regions, contributing to research on neuropeptide regulation of neurotrophic signaling.

0303 areas

Enkephalin Metabolism

Research has examined Selank's effects on the activity of enkephalin-degrading enzymes (enkephalinases), suggesting a potential mechanism for extending the activity of endogenous opioid peptides in preclinical models.

Methodology

How Selank Nasal Spray is studied

  1. 01Method 1Neurobiological studies examine Selank's effects on gene and protein expression in brain tissue, quantifying BDNF, GABA receptor subunit levels, and…+

    Neurobiological studies examine Selank's effects on gene and protein expression in brain tissue, quantifying BDNF, GABA receptor subunit levels, and enkephalin-degrading enzyme activity via RT-PCR, Western blot, and fluorometric enzyme assays. These studies map the molecular correlates of observed behavioral effects.

  2. 02Method 2In vitro studies apply Selank to cultured neuronal cells and immune cells to characterize direct cellular effects independent of whole-organism…+

    In vitro studies apply Selank to cultured neuronal cells and immune cells to characterize direct cellular effects independent of whole-organism pharmacokinetics, providing mechanistic data on receptor interactions and intracellular signaling responses.

Storage protocols

Selank Nasal Spray storage and handling

Full handling protocol+

Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.

Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.

Ordering & shipping

Buy Selank Nasal Spray online

Selank Nasal Spray for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $85. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.

Selank Nasal Spray is supplied as solution in a metered spray bottle, for laboratory and research use only, not for human consumption.

FAQ

Selank Nasal Spray FAQ

What format is Selank Nasal Spray?
Selank is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute. It is sold for laboratory research.
Is Selank Nasal Spray for human use?
No. Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Is a batch report available for Selank Nasal Spray?
A batch report is not yet published for this format. Contact ORP before ordering if you need one.
What is the structural relationship between Selank and tuftsin?
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic analog of tuftsin (Thr-Lys-Pro-Arg), an endogenous immunomodulatory tetrapeptide. The C-terminal Pro-Gly-Pro extension was added to increase metabolic stability by conferring resistance to proteolytic degradation compared to the parent sequence.
What animal models are used in Selank research?
Preclinical research commonly uses rat and mouse models with standardized behavioral paradigms including the elevated plus maze, open field test, and conflict-based anxiety tests. These provide quantitative behavioral endpoints for assessing anxiolytic-like activity under controlled laboratory conditions.
Research library

Selank Nasal Spray research guides

Optimum ReGen Peptides
Optimum ReGen Peptides

Optimum ReGen Peptides provides high-quality peptide compounds for laboratory research applications. All research products, including all peptides, are strictly for research purposes only and are not intended for human consumption.

Research products are intended for laboratory research purposes only. Not for human consumption. Our tallow skincare products are topical cosmetics for external use only. No product is intended to diagnose, treat, cure, or prevent any disease.

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