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DSIP/Pinealon Nasal Spray

DSIP/Pinealon is a research blend of DSIP and Pinealon, studied in sleep and neurological research, supplied as a research nasal spray.

$130
Presale · ships by Mon, Nov 92-Day Priority Air anywhere in the US

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  • Presale: orders ship from Nov 9.
  • 2-Day Priority Air: $13 flat anywhere in the US, or pick up in Medford.
  • Tracking is emailed the moment your order ships.
  • Research compounds are final sale; see the refund policy.
Lab sheet

DSIP/Pinealon Nasal Spray details

Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.

Certificate of analysis
Not published yet

A third-party certificate for DSIP/Pinealon Nasal Spray is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.

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Molecular Formula
C35H48N10O15
Molar Mass
848.8 g/mol
CAS Number
62568-57-4
Form
Solution in a metered spray bottle
Full data sheet+
Sizes
Nasal spray
Purity
A batch report is not yet published for this format. Contact ORP before ordering if you need one.

For research use only. Not for human consumption.

Overview

About DSIP/Pinealon Nasal Spray

DSIP/Pinealon is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute.

Read more

The name delta sleep-inducing peptide reflects the peptide's original 1974 characterization by Monnier and colleagues, whose electrical-stimulation studies in rabbits linked cerebral venous extracts to delta-wave, or slow-wave, EEG activity associated with deep non-REM sleep stages. Subsequent laboratory work has focused less on reproducing that original observation and more on mapping how DSIP interacts with the systems that regulate circadian and ultradian rhythm in animal research models. Researchers frequently note that the sleep-inducing portion of the name describes the historical research context of its discovery rather than a demonstrated effect in any species, including humans.

DSIP peptide research today is concentrated in a handful of recurring model systems: rodent EEG and sleep-stage recording, isolated hypothalamic-pituitary tissue and cell-culture assays, and plasma stability and protein-binding studies. Much of the published literature approaches DSIP less as a single-mechanism peptide and more as a signaling molecule with multiple, still-debated points of interaction across the neuroendocrine system. This breadth is part of why DSIP continues to appear in comparative-peptide panels alongside other short neuropeptides studied for hypothalamic and pituitary signaling.

Documented DSIP research applications include studies of opioid-tolerance and withdrawal models, stress-response and gastric stress-ulcer models in rodents, chronobiology and circadian-rhythm research, and early radioprotection studies examining peptide behavior under radiation exposure in animal tissue. Each of these lines of investigation uses DSIP as a tool compound to probe a specific physiological pathway rather than as a single-purpose research subject. Researchers comparing findings across these application areas typically note that DSIP's effects appear model-dependent, varying with concentration, tissue type, and experimental timing in ways that are still being mapped in the literature.

Pinealon is a short synthetic peptide examined in neurological research models; here it is combined with DSIP in a single research solution.

Research context

What DSIP/Pinealon Nasal Spray is researched for

The areas where this compound appears in the published research literature.

0103 areas

Sleep physiology and EEG research

DSIP was originally characterized by its ability to induce delta wave activity in EEG recordings in rabbit models. Laboratory studies have continued to investigate its role in sleep-wake cycle regulation and its interactions with endogenous sleep-promoting systems.

0203 areas

HPA axis and stress response modulation

Research has examined DSIP's interactions with corticotropin-releasing hormone (CRH) and ACTH pathways, with investigators studying how the peptide influences stress hormone cascades in both in vitro and animal model systems.

0303 areas

Neuroendocrine signaling

Studies have investigated DSIP's effects on gonadotropin release, growth hormone secretion, and other pituitary hormone dynamics in research models, positioning it as a compound of interest in neuroendocrine axis research.

Methodology

How DSIP/Pinealon Nasal Spray is studied

  1. 01Method 1Classical DSIP research employs EEG telemetry in freely moving rodents or rabbits, with continuous electrophysiological recording used to quantify changes in sleep architecture following peptide administration.+

    Classical DSIP research employs EEG telemetry in freely moving rodents or rabbits, with continuous electrophysiological recording used to quantify changes in sleep architecture following peptide administration. Power spectral analysis of EEG frequency bands allows researchers to objectively characterize delta, theta, and spindle activity in treated versus control animals.

  2. 02Method 2Neuroendocrine experiments use pituitary cell cultures (GH3, AtT-20) and primary pituitary tissue explants to measure peptide release in response to DSIP.+

    Neuroendocrine experiments use pituitary cell cultures (GH3, AtT-20) and primary pituitary tissue explants to measure peptide release in response to DSIP. Mass spectrometry-based peptide profiling and protein expression panels help researchers map DSIP's interactions with hormone-secreting cell populations at the molecular level.

Storage protocols

DSIP/Pinealon Nasal Spray storage and handling

Full handling protocol+

Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.

Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.

Ordering & shipping

Buy DSIP/Pinealon Nasal Spray online

DSIP/Pinealon Nasal Spray for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $130. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.

DSIP/Pinealon Nasal Spray is supplied as solution in a metered spray bottle, for laboratory and research use only, not for human consumption.

FAQ

DSIP/Pinealon Nasal Spray FAQ

What format is DSIP/Pinealon Nasal Spray?
DSIP/Pinealon is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute. It is sold for laboratory research.
Is DSIP/Pinealon Nasal Spray for human use?
No. Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Is a batch report available for DSIP/Pinealon Nasal Spray?
A batch report is not yet published for this format. Contact ORP before ordering if you need one.
What is DSIP peptide?
DSIP (delta sleep-inducing peptide) is a synthetic nonapeptide, sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, supplied to laboratories for research into sleep-stage neurophysiology and neuroendocrine signaling. It is sold strictly for laboratory research use and is not for human consumption.
What is delta sleep-inducing peptide?
Delta sleep-inducing peptide is the full name behind the DSIP abbreviation, referencing the nonapeptide's original 1974 characterization in rabbit studies that linked cerebral venous extracts to delta-wave EEG activity during non-REM sleep research models. The name reflects that historical research context rather than a demonstrated effect in any species.
Research library

DSIP/Pinealon Nasal Spray research guides

Optimum ReGen Peptides
Optimum ReGen Peptides

Optimum ReGen Peptides provides high-quality peptide compounds for laboratory research applications. All research products, including all peptides, are strictly for research purposes only and are not intended for human consumption.

Research products are intended for laboratory research purposes only. Not for human consumption. Our tallow skincare products are topical cosmetics for external use only. No product is intended to diagnose, treat, cure, or prevent any disease.

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