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Semax is a synthetic ACTH(4-7) analogue heptapeptide studied in neurological research, supplied as a research nasal spray.
New product line: orders ship from Nov 9, then 2-Day Priority Air.
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Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.
A third-party certificate for Semax Nasal Spray is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.
Ask about a certificateFor research use only. Not for human consumption.
Semax is supplied in solution in a metered spray bottle. The solution is ready to use, so there is nothing to reconstitute.
Semax is a heptapeptide analog of the ACTH(4-7) fragment with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Developed in Russia at the Institute of Molecular Genetics of the Russian Academy of Sciences, Semax was designed to retain the cognitive and neuroprotective properties associated with ACTH-derived peptides while eliminating their steroidogenic activity. It has been studied extensively in neuroscience research contexts.
Laboratory investigations have characterized Semax's interactions with the brain-derived neurotrophic factor (BDNF) signaling pathway. In rodent model studies, Semax exposure has been associated with increased BDNF and TrkB mRNA expression in hippocampal and cortical tissue, placing it within the growing field of neurotrophic factor research. Researchers have also examined its reported modulation of dopaminergic and serotonergic markers in preclinical neural models.
The areas where this compound appears in the published research literature.
In vitro, Semax is applied to primary cortical neuron cultures and neural stem cell preparations. Researchers measure neuronal survival following oxidative stress or excitotoxic challenge using MTT/resazurin viability assays, caspase activation profiling, and mitochondrial membrane potential indicators. TrkB pathway phosphorylation status is assessed by Western blot.
Rodent behavioral studies complement biochemical endpoints. Researchers use standardized paradigms to quantify performance across treatment groups, and statistical analysis includes ANOVA with post-hoc correction. Semax's effect duration in behavioral models is a specific focus of pharmacodynamic research investigating the relationship between peripheral administration timing and CNS endpoint windows.
Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.
Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Semax Nasal Spray for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $85. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
Semax Nasal Spray is supplied as solution in a metered spray bottle, for laboratory and research use only, not for human consumption.
