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For laboratory research use only.
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Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.
A third-party certificate for MT-2 is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.
Ask about a certificateFor research use only. Not for human consumption.
MT-2 (Melanotan II) is a synthetic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), a naturally occurring neuropeptide derived from the proopiomelanocortin (POMC) precursor. It acts as a non-selective agonist at melanocortin receptors (MC1R through MC5R), with particular research interest focused on its activity at MC1R, MC3R, and MC4R subtypes.
The melanocortin system is involved in a diverse range of physiological processes studied in the laboratory, including pigmentation pathways, energy homeostasis, immune modulation, and reproductive biology. MT-2 has been widely used as a pharmacological probe to dissect the contributions of individual melanocortin receptor subtypes to these systems in preclinical research.
MT-2 is a research compound intended exclusively for laboratory investigation. It is not approved for human or veterinary therapeutic use, and all research involving this peptide must be conducted under appropriate institutional oversight and in compliance with applicable regulations.
The areas where this compound appears in the published research literature.
In cell culture systems, MT-2 is applied to receptor-expressing cell lines at defined concentrations to generate concentration-response curves for cAMP accumulation and receptor internalization, providing data on potency and efficacy at each MC receptor subtype.
In vivo rodent studies have been used to investigate the behavioral and physiological effects of MC receptor activation. Central administration (intracerebroventricular) and peripheral administration designs allow researchers to distinguish central from peripheral contributions to observed outcomes.
Competitive binding assays using radiolabeled or fluorescent ligands characterize MT-2's affinity across the five MC receptor subtypes, providing selectivity data that guides interpretation of in vivo findings and comparison to more selective tool compounds.
Store lyophilized MT-2 at -20 C or below, protected from light and moisture. The lyophilized form is stable for extended periods under these conditions. Reconstitute in bacteriostatic water or sterile saline using standard aseptic technique. Store reconstituted solutions at 4 C for short-term use or aliquot and freeze at -80 C. Minimize freeze-thaw cycles to preserve peptide integrity. All storage and handling should adhere to institutional biosafety and chemical hygiene protocols.
MT-2 (Melanotan II) for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $50. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
MT-2 is supplied as lyophilized powder, for laboratory and research use only, not for human consumption.
