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For laboratory research. Sold in 5mg and 50mg sizes.
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For research use only. Not for human consumption.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) that selectively activates the growth hormone secretagogue receptor (GHSR-1a, also known as the ghrelin receptor). It was developed as a research tool to investigate the pituitary growth hormone axis with a high degree of receptor selectivity, distinguishing it from earlier GHS compounds that also stimulated ACTH and cortisol secretion.
In preclinical research, ipamorelin has been studied for its effects on pulsatile growth hormone release, its interactions with the hypothalamic-pituitary axis, and the downstream signaling cascades initiated by GHSR-1a activation. Its selectivity profile makes it particularly useful for researchers seeking to isolate GH-axis effects without confounding corticotroph stimulation.
Ipamorelin is a research compound used exclusively in laboratory settings. It is not approved for human therapeutic use, and all work involving this peptide must be conducted under appropriate institutional and regulatory oversight.
The areas where this compound appears in the published research literature.
In pituitary cell culture assays, ipamorelin is applied at nanomolar concentrations to assess GH secretion via radioimmunoassay or ELISA. Selectivity against ACTH secretion is measured in parallel corticotroph preparations, establishing the compound's functional specificity profile.
In vivo rodent studies use serial blood sampling to characterize the GH secretory pulse. Pharmacokinetic/pharmacodynamic modeling is used to relate plasma ipamorelin concentrations to GH release profiles over time.
Molecular studies use GHSR-1a-transfected cell lines to measure receptor binding affinity (Ki), functional cAMP accumulation, and beta-arrestin recruitment in order to understand ipamorelin's signaling bias relative to native ghrelin.
Store lyophilized ipamorelin at -20 C or below, protected from moisture and light. The lyophilized form is stable under these conditions for extended periods. Once reconstituted in bacteriostatic water or sterile saline, store at 4 C for short-term use (up to 2-4 weeks based on published stability data) or aliquot and store at -80 C for longer retention. Minimize freeze-thaw cycles, which can promote peptide aggregation. Document all reconstitution and storage conditions per laboratory quality standards.
Ipamorelin for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $45. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
The current batch has a published third-party certificate of analysis, shown above. Ipamorelin is supplied as lyophilized powder, for laboratory and research use only, not for human consumption.
