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BPC-157 / TB-500

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BPC-157 / TB-500 Research Stack.

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This dual-peptide preparation contains BPC-157 (Body Protective Compound-157) and TB-500 (Thymosin Beta-4 fragment), two compounds frequently co-investigated in tissue repair and cellular migration research models. BPC-157 is studied for its roles in growth factor signaling and angiogenesis; TB-500 is researched for its actin-binding properties and effects on cellular motility in laboratory settings. Researchers combine these peptides to evaluate potential synergistic interactions across overlapping molecular pathways in preclinical assay systems. Supplied as a co-lyophilized blend of 5mg each at analytical purity. For laboratory research use only; reconstitute under sterile conditions.

Why you'll like it
  • 5mg / 5mg dual format
  • Research-grade formulation
  • Sealed vials
≥99%
HPLC purity
Certificate of analysis
Third-party tested. Every batch.

Independently verified by Freedom Diagnostics via HPLC and mass spec. Every vial carries a unique accession number you can look up directly with the lab.

Verify COA · Freedom Diagnostics
In every order
Peptide vial(s)
Alcohol prep pads
Storage guide
Shipping & returns
  • 2-day shipping nationwide, flat $12.50
  • Plain, discreet packaging. No product names on the outside.
  • Tracking emailed the moment your order ships.
Form
Lyophilized powder (blend)
Overview

About BPC-157 / TB-500

This research blend combines BPC-157 (Body Protection Compound-157) and TB-500 (a synthetic peptide derived from the thymosin beta-4 sequence) in equal 5 mg portions. BPC-157 is a pentadecapeptide identified in research on gastric mucosal proteins, while TB-500 is studied as an actin-sequestering peptide investigated in connective tissue biology and wound-healing models. Together, researchers combine them to examine potential complementary mechanisms in preclinical model systems.

BPC-157 has been extensively characterized in rodent models where researchers have studied its interactions with growth hormone receptor signaling, nitric oxide pathways, and musculoskeletal tissue endpoints. TB-500 research has focused on its actin-binding domain and its reported involvement in cell migration, angiogenesis marker expression, and extracellular matrix remodeling observed in laboratory cell culture systems.

This combined formulation is prepared for laboratory use only. Researchers handling this blend should follow standard peptide handling procedures including cold-chain storage, sterile reconstitution technique, and proper laboratory safety protocols. The compound is not intended for administration to humans or animals outside of formally approved preclinical study frameworks.

Ordering & shipping

Buy BPC-157 / TB-500 online

BPC-157 / TB-500 is in stock and available to buy online from Optimum ReGen Peptides — a real American research-peptide company with a physical storefront in Medford, Oregon, not an anonymous overseas dropshipper. Priced from $70, every order ships within two business days, flat $12.50 nationwide, in plain discreet packaging with tracking.

As your BPC-157 / TB-500 supplier we back every batch with a third-party certificate of analysis and compound in a licensed US 503A pharmacy. Vials are supplied lyophilized at analytical purity for laboratory and research use only, not for human consumption.

Research context

Researched For

01
Connective tissue and tendon biology

Both components have been independently studied in models of tendon and ligament injury, with researchers examining cellular proliferation, collagen synthesis markers, and tissue architecture in treated versus control groups.

02
Gastrointestinal mucosal research

BPC-157 in particular has been extensively investigated in rodent gastrointestinal models, with laboratory studies examining ulcer-healing endpoints, mucosal blood flow markers, and cytoprotective signaling in gut epithelial cell preparations.

03
Angiogenesis pathway studies

TB-500 research has characterized its interactions with vascular endothelial growth factor (VEGF) expression and endothelial cell tube formation assays, making this blend relevant to angiogenesis mechanism research.

04
Muscle satellite cell biology

Preclinical studies have used both compounds in skeletal muscle injury models, studying satellite cell activation markers, myosin heavy chain expression patterns, and regenerative index endpoints.

05
Neurological tissue models

Laboratory investigations have explored BPC-157 interactions with dopaminergic and serotonergic systems in rodent brain tissue, and researchers have studied TB-500 in spinal cord injury models examining motor function endpoints.

Methodology

How It Is Studied

In preclinical research, BPC-157 is typically administered via subcutaneous injection or oral gavage in rodent models, enabling researchers to compare systemic versus local delivery effects on target tissue endpoints. Standard readouts include histological scoring of tissue sections, immunohistochemical staining for repair-associated markers, and quantitative PCR for growth factor gene expression.

TB-500 studies frequently use scratch assay and transwell migration protocols in vitro to characterize its effects on cell motility. In vivo rodent wound models employ planimetry, tensiometry, and immunofluorescence imaging to quantify tissue repair endpoints. When studied in combination with BPC-157, researchers typically use factorial experimental designs to distinguish additive or synergistic interaction effects.

Reconstitution of this blend is performed in sterile bacteriostatic water or saline. Researchers prepare fresh aliquots for each experimental run, document concentration calculations carefully, and confirm peptide identity by mass spectrometry prior to use in formal study protocols.

Technical sheet

Specifications

Technical data sheetResearch grade
FormLyophilized powder (blend)
BPC-157 content5 mg per vial
TB-500 content5 mg per vial
Purity>= 99% (HPLC, each component)
BPC-157 Molecular FormulaC62H98N16O22
TB-500 Sequence originThymosin beta-4 fragment (Ac-LKKTETQ)
For research use only. Not for human consumption.
Storage protocols

Storage & Handling

The lyophilized blend should be stored at -20 °C in a dry, light-protected environment. Under these conditions, the powder is stable for the duration of the labeled shelf life. Following reconstitution in sterile bacteriostatic water, the solution should be held at 4 °C and used within 7 to 10 days.

Pre-aliquoting prior to reconstitution is recommended to limit freeze-thaw cycles. Researchers should label vials with reconstitution date, lot number, and concentration. Discard any solution that appears cloudy, discolored, or shows particulate matter.

FAQ

Frequently Asked Questions

Why is BPC-157 combined with TB-500 in research?+
Researchers combine these peptides to investigate whether their distinct mechanisms, BPC-157 acting through growth hormone receptor and nitric oxide pathways and TB-500 through actin-sequestration and cell migration signaling, produce complementary or additive effects in tissue repair model endpoints.
Are BPC-157 and TB-500 naturally occurring compounds?+
BPC-157 is a synthetic pentadecapeptide with a sequence derived from human gastric juice proteins. TB-500 is a synthetic analog of a conserved region of thymosin beta-4, a naturally occurring actin-binding protein found in most mammalian cells.
What is the difference between TB-500 and thymosin beta-4?+
TB-500 represents a specific active fragment of the full thymosin beta-4 protein. Researchers use TB-500 to study the actin-sequestering domain in isolation, allowing mechanistic dissection of the full protein's biological activities.
How should this blend be reconstituted for laboratory use?+
Sterile bacteriostatic water is the most commonly used reconstitution vehicle for this blend in research settings. The researcher determines the appropriate volume based on the desired working concentration for the specific experimental protocol.
Is this product suitable for human research?+
No. This product is a laboratory research compound only and is not approved, certified, or intended for human administration or clinical investigation.
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Research library

BPC-157 / TB-500 research guides