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BPC‑157

For laboratory research. Sold in 5mg, 10mg and 50mg kit sizes.

$24.15
$3531% off
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Lab sheet

BPC-157 details

Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.

Certificate of analysis
Not published yet

A third-party certificate for BPC-157 is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.

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Molecular Formula
C62H98N16O22
Molar Mass
1419.5 g/mol
CAS Number
137525-51-0
Form
Lyophilized powder
Full data sheet+
Purity
See the available batch report for the tested sample's purity. Confirm the product and lot before ordering.

For research use only. Not for human consumption.

Overview

About BPC-157

BPC-157 (Body Protection Compound-157) is a pentadecapeptide consisting of 15 amino acids, derived from a partial sequence of human gastric juice protein BPC. It was first described in the early 1990s, and since then has been extensively studied in preclinical models for its effects on tissue repair, angiogenesis, and gastrointestinal function.

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A substantial body of peer-reviewed research, largely conducted in rodent models, has investigated BPC-157's interactions with the nitric oxide (NO) system, growth hormone receptors, and vascular endothelial growth factor (VEGF) pathways. These studies have examined its stability in gastric acid and its systemic availability following different routes of administration in controlled laboratory settings.

BPC-157 has attracted significant scientific attention due to its apparent multi-tissue activity in research models, with studies spanning tendon, muscle, bone, nerve, and gastrointestinal tissue. Its mechanism of action remains an active area of investigation, with researchers exploring interactions between this peptide and multiple signaling networks involved in cellular repair and cytoprotection.

Research context

What BPC-157 is researched for

The areas where this compound appears in the published research literature.

0105 areas

Tendon and ligament repair models

BPC-157 has been among the most frequently studied peptides in tendon healing research, with numerous animal studies examining how it affects fibroblast proliferation, collagen organization, and the speed of structural repair in severed or damaged tendon tissue.

0205 areas

Gastrointestinal mucosal integrity

Research has studied BPC-157 in models of gastric ulceration, inflammatory bowel conditions, and intestinal anastomosis, investigating its cytoprotective properties and interactions with the gut lining at the cellular level.

0305 areas

Angiogenesis and vascular research

Laboratory studies have examined BPC-157's role in stimulating new blood vessel formation, with researchers investigating its modulation of VEGF expression and endothelial cell activity in wound healing and ischemia models.

0405 areas

Muscle tissue research

Multiple preclinical studies have investigated BPC-157 in crush injury and transection muscle models, examining myocyte repair kinetics, satellite cell activity, and functional recovery metrics in controlled laboratory settings.

0505 areas

Neurological and nerve repair models

Investigators have studied BPC-157 in peripheral and central nervous system injury models, examining axonal regeneration rates, neuroprotective markers, and behavioral outcomes in animal subjects under research protocols.

Methodology

How BPC-157 is studied

  1. 01Method 1BPC-157 research in tendon and muscle models typically involves surgical transection or crush injury in rodents, followed by localized or systemic administration of the peptide.+

    BPC-157 research in tendon and muscle models typically involves surgical transection or crush injury in rodents, followed by localized or systemic administration of the peptide. Outcome measures include biomechanical tensile strength testing of repaired tissue, histological scoring of collagen fiber organization, and immunohistochemical staining for fibroblast and endothelial cell markers.

  2. 02Method 2Gastrointestinal studies employ chemically induced lesion models (cysteamine, indomethacin, alcohol) in rats, with BPC-157 administered before or after injury.+

    Gastrointestinal studies employ chemically induced lesion models (cysteamine, indomethacin, alcohol) in rats, with BPC-157 administered before or after injury. Researchers measure lesion area via endoscopic or gross pathology examination, alongside molecular markers of inflammation such as TNF-alpha, IL-1 beta, and COX-2 expression in gastric tissue samples.

  3. 03Method 3Angiogenesis experiments use tube formation assays in human umbilical vein endothelial cells (HUVECs), matrigel plug assays in mice, and VEGF protein…+

    Angiogenesis experiments use tube formation assays in human umbilical vein endothelial cells (HUVECs), matrigel plug assays in mice, and VEGF protein quantification via Western blot to characterize BPC-157's vascular effects. Researchers compare dose-dependent responses to establish concentration-effect relationships in these in vitro systems.

Storage protocols

BPC-157 storage and handling

Lyophilized
-20°C
Long-term storage, as supplied
Reconstituted
4°C
In solution
Use within
48h
Once reconstituted
Full handling protocol+

Lyophilized BPC-157 research material should be stored at -20°C, kept away from humidity and UV exposure. The peptide is stable for extended periods in this state when the vial remains sealed and the cold chain is maintained.

After reconstitution in a sterile aqueous vehicle for laboratory use, BPC-157 solutions should be held at 4°C and used within 48 hours. Repeated freeze-thaw cycles compromise peptide integrity; single-use aliquots are the standard laboratory practice to maintain experimental reproducibility.

Ordering & shipping

Buy BPC-157 online

BPC-157 (Body Protection Compound 157) for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $35. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.

BPC-157 is supplied as lyophilized powder, for laboratory and research use only, not for human consumption.

FAQ

BPC-157 FAQ

How extensive is the published research on BPC-157?
BPC-157 has one of the largest preclinical research profiles among synthetic peptides, with hundreds of peer-reviewed studies published primarily in rodent models. Research spans gastrointestinal, musculoskeletal, and neurological injury models. All published work is preclinical in nature.
What is the proposed mechanism of action studied in BPC-157 research?
Researchers have investigated multiple pathways, including modulation of the nitric oxide system, upregulation of VEGF and its receptors, interaction with growth hormone receptor signaling, and effects on FAK-paxillin and MAPK pathways involved in cell migration and proliferation.
Is BPC-157 naturally occurring?
BPC-157 is a synthetic analog derived from a partial sequence of a protein found in human gastric juice. The parent protein has been characterized in gastric tissue, and BPC-157 represents a stable, synthesized fragment designed for laboratory investigation.
What routes of administration are used in BPC-157 research?
Preclinical studies in animal models compare systemic and localized effects. Route comparisons are a significant component of the published literature.
Are there published safety studies on BPC-157 in animal models?
Yes, several preclinical toxicology studies have examined BPC-157 in rodent models and have not identified significant adverse effects at research-relevant concentrations. These are animal model findings and do not predict human outcomes.
Research library

BPC-157 research guides

Optimum ReGen Peptides
Optimum ReGen Peptides

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