0104 areas
Neuronal survival in culture
Reported neurotrophic-like effects on neuronal survival and neurite outgrowth in cell culture.
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Cerebrolysin (CBL) Research Preparation
A porcine brain peptide preparation, lyophilized. Sold in 60mg vials for laboratory research.
$48.00
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Lab sheet
Cerebrolysin details
Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.
CAS Number
12656-61-0
Form
Lyophilized powder
Full data sheet+
- Purity
- A batch report is not published for this product. Contact ORP before ordering if you need one.
- Composition
- Low-molecular-weight peptides and free amino acids from enzymatic digestion of porcine brain protein
- Source
- Porcine (pig) brain protein
- Synonyms
- Cerebrolysin, CBL, FPF 1070
- Storage (lyophilized)
- -20 °C, sealed, light-protected
For research use only. Not for human consumption.
Overview
About Cerebrolysin
Cerebrolysin is a peptide preparation derived from pig brain protein. Unlike most compounds in this catalog it is not a single molecule: it is a mixture of short peptides and free amino acids produced by enzymatic digestion, studied in laboratory research on neuronal survival and brain-injury models.
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Because it is a mixture, it has no single amino acid sequence, molecular formula or molar mass. Its CAS number, 12656-61-0, identifies the preparation as a whole. ORP supplies it as a lyophilized powder in 60mg vials for in vitro and preclinical research only. It is not for human or animal use and is not intended to diagnose, treat, cure, or prevent any disease.
The preparation is made by controlled proteolytic digestion of purified porcine brain proteins, keeping the low-molecular-weight fraction of peptides and free amino acids. In a 2015 study in Drug Testing and Analysis, researchers at Ghent University used liquid chromatography and mass spectrometry to identify 638 distinct peptides in a Cerebrolysin sample, most of them fragments of tubulin, actin and myelin basic protein. They found no fragments of known neurotrophic factors such as BDNF, NGF or GDNF.
The name Cerebrolysin also belongs to a medicine made by EVER Pharma in Austria and registered in a number of countries outside the United States, where it is supplied as a ready-made solution in ampoules. It is not approved by the FDA. This listing is a lyophilized research preparation for laboratory use, not that licensed medicinal product.
Laboratory research on Cerebrolysin has looked at reported neurotrophic-like effects on neuronal survival and neurite outgrowth in cell culture, and at rodent models of ischemic stroke, traumatic brain injury and neurodegeneration.
Because Cerebrolysin is a mixture, a single HPLC purity figure or a single-mass identity check does not describe it the way it does a defined peptide; characterization relies on peptide profiling and amino acid analysis. A third-party certificate of analysis is not published here for this product; contact ORP before ordering if your work needs particular tests.
Research context
What Cerebrolysin is researched for
The areas where this compound appears in the published research literature.
Methodology
How Cerebrolysin is studied
01Method 1Published Cerebrolysin work uses primary neuronal and neural progenitor cultures, with readouts such as cell survival and neurite outgrowth, and rodent models…+
Published Cerebrolysin work uses primary neuronal and neural progenitor cultures, with readouts such as cell survival and neurite outgrowth, and rodent models of stroke, brain injury and neurodegeneration, with histology and behavioral scoring.
02Method 2Because the material is a mixture, researchers characterize it by peptide profiling and amino acid analysis rather than against a single sequence.+
Because the material is a mixture, researchers characterize it by peptide profiling and amino acid analysis rather than against a single sequence. Each research protocol sets its own model, controls, concentrations and handling; this listing supplies the compound, not a protocol.
Storage protocols
Cerebrolysin storage and handling
Lyophilized
-20°C
Long-term storage, as supplied
Reconstituted
2-8°C
In solution
Full handling protocol+
Store lyophilized Cerebrolysin at -20°C, sealed and protected from light and moisture. Let the vial reach room temperature before opening so moisture does not condense on the powder.
Reconstituted peptide solutions are commonly held at 2-8°C and divided into single-use aliquots to avoid repeated freeze-thaw cycles. Validate the solvent, concentration and use period for your own protocol.
Ordering & shipping
Buy Cerebrolysin online
Cerebrolysin for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $60. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
Cerebrolysin is supplied as lyophilized powder, for laboratory and research use only, not for human consumption.
FAQ
Cerebrolysin FAQ
What is Cerebrolysin?
Cerebrolysin is a peptide preparation made by enzymatic digestion of purified pig brain proteins: a mixture of short peptides and free amino acids, studied in neuronal culture and brain-injury research. ORP sells it for laboratory research only.
Does Cerebrolysin have an amino acid sequence or molecular formula?
Not a single one. It is a mixture of many peptides plus free amino acids, so it has no single sequence, formula or molar mass. A 2015 mass spectrometry study identified 638 distinct peptides in one sample.
What is the CAS number for Cerebrolysin?
12656-61-0. The number identifies the preparation as a whole, not a single molecule. Its FDA UNII code is 37KZM6S21G.
What does CBL 60 mean?
CBL is a common shorthand for Cerebrolysin, and 60 refers to the 60mg vial size. This listing is the 60mg lyophilized vial.
Is this the same as the Cerebrolysin medicine?
No. Cerebrolysin is also the name of a medicine made by EVER Pharma, registered in a number of countries outside the United States and supplied as a ready-made solution in ampoules. It is not FDA-approved. This listing is a lyophilized research preparation for laboratory use.
What does Cerebrolysin research study?
Mainly reported neurotrophic-like effects on neurons in culture, and recovery in rodent models of ischemic stroke, traumatic brain injury and neurodegeneration. All of this is laboratory research in cell and animal models.
Is this Cerebrolysin third-party tested?
A third-party certificate of analysis is not published for this product. Contact ORP before ordering if your work needs particular identity or purity tests.
How should Cerebrolysin be stored?
Keep the lyophilized powder at -20°C, sealed and protected from light and moisture. Reconstituted solutions are commonly kept at 2-8°C in single-use aliquots; validate the use period for your own protocol.
Is Cerebrolysin for human use?
No. ORP sells Cerebrolysin strictly as a laboratory research compound, not for human or animal consumption, and it is not intended to diagnose, treat, cure, or prevent any disease.
Research library