0103 areas
Fibroblast and extracellular matrix biology
Laboratory studies have investigated GHK-Cu's ability to stimulate fibroblast migration and proliferation, and to influence collagen and glycosaminoglycan synthesis in cell culture models.
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GHK‑Cu Oral Thin Film
GHK-Cu is the copper-binding tripeptide studied in tissue-repair and skin research, supplied as a research oral thin film.
$175
Presale · ships by Mon, Nov 92-Day Priority Air anywhere in the US
New product line: orders ship from Nov 9, then 2-Day Priority Air.
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Shipping & returns
- Presale: orders ship from Nov 9.
- 2-Day Priority Air: $13 flat anywhere in the US, or pick up in Medford.
- Tracking is emailed the moment your order ships.
- Research compounds are final sale; see the refund policy.
Lab sheet
GHK-Cu Oral Thin Film details
Identity, purity and handling data for this compound, in one place. Tap an identifier to copy it.
Certificate of analysis
Not published yet
A third-party certificate for GHK-Cu Oral Thin Film is not published here yet. If your work needs one, ask us before ordering and we will tell you what testing is available for the current lot.
Ask about a certificateMolecular Formula
C14H23CuN6O4
Molar Mass
403.91 g/mol
CAS Number
89030-95-5
Form
Oral thin film (OTF), boxed
Full data sheet+
- Sizes
- 30 Day Supply
- Purity
- A batch report is not yet published for this format. Contact ORP before ordering if you need one.
For research use only. Not for human consumption.
Overview
About GHK-Cu Oral Thin Film
GHK-Cu is supplied in oral thin film (OTF) format: thin, dissolvable film strips packed in a box.
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GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a naturally occurring tripeptide-copper complex first isolated from human plasma. It is found in saliva, urine, and various tissues and its concentrations in plasma decline with age. The compound has been extensively studied in cell biology and wound-healing research for its interactions with copper-binding proteins and its reported influence on gene expression profiles.
Research published over several decades indicates that GHK-Cu modulates a broad array of biological processes at the cellular level. Studies have examined its effects on fibroblast activity, extracellular matrix remodeling, antioxidant enzyme expression, and angiogenesis-related signaling pathways. Its small size and copper-chelating structure facilitate cellular uptake in laboratory models.
As a research compound, GHK-Cu is investigated in contexts ranging from tissue biology to skin model research and gene regulation studies. It is intended strictly for laboratory use and is not approved as a pharmaceutical or therapeutic agent.
Research context
What GHK-Cu Oral Thin Film is researched for
The areas where this compound appears in the published research literature.
Methodology
How GHK-Cu Oral Thin Film is studied
01Method 1In cell culture systems, GHK-Cu is typically applied to fibroblast or keratinocyte monolayers at nanomolar to micromolar concentrations.+
In cell culture systems, GHK-Cu is typically applied to fibroblast or keratinocyte monolayers at nanomolar to micromolar concentrations. Researchers measure outcomes such as cell proliferation rate, migration assay results, collagen secretion (via ELISA or hydroxyproline assay), and gene expression changes via quantitative PCR or transcriptomics.
02Method 2Animal models of wound healing have been employed to assess how GHK-Cu applied to wound sites influences closure rates, tissue architecture, and collagen deposition histologically.+
Animal models of wound healing have been employed to assess how GHK-Cu applied to wound sites influences closure rates, tissue architecture, and collagen deposition histologically. These models help contextualize the in vitro findings within a more complex biological environment.
Storage protocols
GHK-Cu Oral Thin Film storage and handling
Full handling protocol+
Keep the package sealed and store it as labeled on the product, away from heat, direct light and moisture.
Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Ordering & shipping
Buy GHK-Cu Oral Thin Film online
GHK-Cu Oral Thin Film for sale from Optimum ReGen Peptides, a US research-peptide company with a storefront in Medford, Oregon. It is in stock, priced from $175. Every order ships 2-Day Priority Air, a $13 flat rate anywhere in the US, with tracking, or can be picked up at the store.
GHK-Cu Oral Thin Film is supplied as oral thin film (otf), boxed, for laboratory and research use only, not for human consumption.
FAQ
GHK-Cu Oral Thin Film FAQ
What format is GHK-Cu Oral Thin Film?
GHK-Cu is supplied in oral thin film (OTF) format: thin, dissolvable film strips packed in a box. It is sold for laboratory research.
Is GHK-Cu Oral Thin Film for human use?
No. Supplied for laboratory research use only. Not for human or animal use, and not intended to diagnose, treat, cure, or prevent any disease.
Is a batch report available for GHK-Cu Oral Thin Film?
A batch report is not yet published for this format. Contact ORP before ordering if you need one.
What is the copper stoichiometry in GHK-Cu?
GHK-Cu coordinates one Cu2+ ion per tripeptide molecule through the terminal amine, imidazole nitrogen of histidine, and peptide backbone nitrogen, forming a square-planar coordination complex that is characteristic of copper-binding tripeptides.
How does GHK-Cu influence gene expression in research models?
Transcriptomic studies have reported that GHK-Cu modulates expression of genes associated with tissue remodeling, inflammation response, and antioxidant pathways. The exact mechanisms are still under investigation in the research literature.
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